CB1 and CB2 Receptors- what makes the endocannabinoid system tick.

CB1 receptors can be found primarily in the brain and nervous system CB1 is the main receptor for THC, a phytocannabinoid (phyto meaning, “of the plant”); and, its twin, anandamide, one of the body’s naturally occurring cannabinoids which THC mirrors. Like a light switch THC activates the CB1 receptor which in turn causes cannabis' psychoactive effects.

• CB2 receptors, found predominantly in the immune system are responsible for modulating cannabis’s anti-inflammatory effects. Inflammation is a hot topic in relation to disease and CB2 has a key immune response.

Graphical Image of CB1 and CB2 Receptors (THC and CBD) throughout the Human Body, CB1-Brain/CNS &CB2- Periphery cells associated with immune response.